Treating Growth Hormone Deficiency

Treating Growth Hormone Deficiency


Growth hormone deficiency can cause numerous medical problems that have been discussed in our previous blog about the subject. 

The question we tackle in this blog is how to treat the deficiency efficiently and safely.

Growth hormone replacement therapy using recombinant human growth hormone has been seen as the best treatment for correcting the deficiency.

However its routine use has been controversial because few clinical studies have been performed to determine the potential risks of long term therapy. 

There are also medico legal issues that have not been resolved 

Some of these issues include

One option is to use GH secretagogues such as Sermorelin or the use of growth hormone releasing peptides (GHRP)


Sermorelin stimulates the production and secretion of GH by the pituitary gland.

Sermorelin has physiologic and clinical advantages over hGH that include:


One more advantage is,  unlike exogenous rhGH which has clinical restrictions in its medical use Sermorelin has no legal restrictions.


Growth Hormone Releasing Peptides also stimulate the pituitary glands natural production of endogenous  human growth hormone.

Synergistic release of GH from the pituitary is initiated when Sermorelin is concurrently administered with a growth hormone releasing peptide.


Dr. Anteneh Roba

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